BDBM490063 (S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amino)-1- oxo-3-(thiophen-2-yl)propan-2-yl)- 5-methoxypicolinamide::US10968172, ID # 19t

SMILES COc1ccc(nc1)C(=O)N[C@@H](Cc1cccs1)C(=O)Nc1ccc(cc1)S(=O)(=O)NC(C)(C)C

InChI Key InChIKey=FYRGZUDOECBKEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490063   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM490063(US10968172, ID # 19t | (S)-N-(1-((4-(N-(tert- buty...)
Affinity DataIC50: 1.04E+3nMAssay Description:The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent