BDBM490156 US10968215, Compound 33::US10968215, Compound 35

SMILES CC(N1CCOCC1)c1c(C)c(cc2cc(cn12)-c1ccccc1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=RQYBQMBUEIRGMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490156   

LigandPNGBDBM490156(US10968215, Compound 33 | US10968215, Compound 35)
Affinity DataIC50: 100nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

LigandPNGBDBM490156(US10968215, Compound 33 | US10968215, Compound 35)
Affinity DataIC50: 100nMAssay Description:EZH2Y641F: PRC2 complex experimental method: Experimental method: PRC2 complex (EZH2 Y641F/EED/SUZ12/RbAp48/AEBP2), H3(1-50) me1 substrate, methyl do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent