BDBM490699 US10968236, Compound I-27

SMILES CCNC(=O)[C@](O)(CC(F)(F)F)c1ccc(Nc2nc(nc3CNC(=O)c23)-c2c(F)cccc2F)cc1

InChI Key InChIKey=WHHAYQWTTQCAKY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490699   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM490699(US10968236, Compound I-27)
Affinity DataKi: <10nMAssay Description:Tyk2 & JAK2: The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM490699(US10968236, Compound I-27)
Affinity DataKi:  55nMAssay Description:Tyk2 & JAK2: The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent