BDBM490898 Ethyl (1s*,4S*)-1-((4-chloro-1-ethyl-5-(2-methoxy-4-(((R)-1,1,1-trifluoropropan-2-yl)amino)phenyl)-1H-pyrazole-3-carboxamido)methyl)-4-(methylsulfonyl)cyclohexane-1-carboxylate::US10975037, Example 94

SMILES CCn1nc(C(=O)NC[C@@]2(CC)CC[C@@H](CC2)S(C)(=O)=O)c(Cl)c1-c1ccc(N[C@H](C)C(F)(F)F)cc1OC

InChI Key InChIKey=VVJTXSDJIFTEJL-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490898   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490898(US10975037, Example 94 | Ethyl (1s*,4S*)-1-((4-chl...)
Affinity DataKd:  0.220nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent