BDBM491171 US10975056, Example 115

SMILES N[C@H]1CCN(C1)c1nc(SC(C(N)=O)c2ccccc2)c(C#N)c(C2CC2)c1C#N

InChI Key InChIKey=XSBOMFPXGIVJLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491171   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491171(US10975056, Example 115)
Affinity DataIC50: 320nMAssay Description:Biochemical activity of DNMT1 analyzed using SPA technology. Plates (Griener 784075) were pre-stamped with 100 nL/well of compound (11-point, 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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