BDBM49122 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propionohydrazide;hydrochloride::2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydrochloride::2-azanyl-3-oxidanyl-N'-[[2,3,4-tris(oxidanyl)phenyl]methyl]propanehydrazide;hydrochloride::BENSERAZIDE HYDROCHLORIDE::Benserazide::MLS000028424::SMR000058421::cid_26964

SMILES NC(CO)C(=O)NNCc1ccc(O)c(O)c1O

InChI Key InChIKey=BNQDCRGUHNALGH-UHFFFAOYSA-N

Data  9 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 49122   

TargetEstrogen receptor beta(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataIC50: 3.05E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataEC50:  3.75E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataEC50:  112nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2011
Entry Details
PCBioAssay
TargetSUMO-conjugating enzyme UBC9(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataIC50: 1.66E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetSUMO-activating enzyme subunit 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataIC50: 2.32E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetIntestinal-type alkaline phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataEC50:  5.47E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetIntestinal-type alkaline phosphatase 1(Rat)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataIC50: 5.09E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataEC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetAlkaline phosphatase, germ cell type(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataEC50:  1.15E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetIntestinal-type alkaline phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataEC50:  8.88E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant Coxsackievirus B3 3C protease expressed in Escherichia coli BL21 (DE3) preincubated for 5 mins followed by addition of NMA-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetHexokinase-2(Human)
Shandong University At Weihai

Curated by ChEMBL
LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataIC50: 5.52E+3nMAssay Description:Inhibition of HK2 (unknown origin) using glucose-6-phosphate dehydrogenase as substrate preincubated for 10 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute For Translational Medicine and Pharmacology (Itmp) and Fraunhofer Cluster of Excellence For Immune Mediated Diseases (Cimd

LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataIC50: 140nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute For Translational Medicine and Pharmacology (Itmp) and Fraunhofer Cluster of Excellence For Immune Mediated Diseases (Cimd

LigandPNGBDBM49122(SMR000058421 | MLS000028424 | 2-amino-3-hydroxy-N'...)
Affinity DataIC50: 180nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details Article