BDBM491832 US10975064, Compound I-22

SMILES CN1c2cc(ccc2OC[C@H](NC(=O)c2n[nH]c(Cc3ccccc3)n2)C1=O)N1CCC2(C1)CCOCC2

InChI Key InChIKey=QEOXZNTVEGDYFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491832   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM491832(US10975064, Compound I-22)
Affinity DataIC50: 23.6nMAssay Description:A 500 ml stock volume of 5× Reaction Kinase Buffer was made by mixing 1000 μl of 1M MgCl2, 500 μl of 1M Tris-HCL pH7.4, 0.5 mg/ml (25 mg) o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent