BDBM491934 (S)-5-(6-(Cyclohexylamino)-4-cyclopropylpyridin-3-yl)-N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-4-(2-methylpiperidine-1-carbonyl)thiazole-2-carboxamide::US10975068, Example 75

SMILES C[C@H]1CCCCN1C(=O)c1nc(sc1-c1cnc(NC2CCCCC2)cc1C1CC1)C(=O)NC1CCS(=O)(=O)CC1

InChI Key InChIKey=YQPMRKKHNJKWFF-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491934   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM491934(US10975068, Example 75 | (S)-5-(6-(Cyclohexylamino...)
Affinity DataKd:  0.230nMAssay Description:1,8-ANS (Invitrogen) was used as a fluorescent dye. Protein and compound solutions are dispensed into black 384-well polypropylene PCR microplates (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent