BDBM492371 US10975080, Example 69

SMILES Cn1c(nc2[nH]nc(-c3ccncc3)c2c1=O)N1CCC2(COC[C@H]2N)CC1

InChI Key InChIKey=YLPOZGAVZNREHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492371   

LigandPNGBDBM492371(US10975080, Example 69)
Affinity DataIC50: 39nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent