BDBM492378 US10975080, Example 76::US10975080, Example 82

SMILES C[C@H]1C[C@@H](N)C2(C1)CCN(CC2)c1nc2[nH]nc(-c3ccnc(N)c3Cl)c2c(=O)n1C

InChI Key InChIKey=SEGPQWQFJSIYBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492378   

LigandPNGBDBM492378(US10975080, Example 76 | US10975080, Example 82)
Affinity DataIC50: 32nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent

LigandPNGBDBM492378(US10975080, Example 76 | US10975080, Example 82)
Affinity DataIC50: 32nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent