BDBM492624 7-((2-chlorobenzyl) thio)-3H-[1,2,3]triazolo [4,5-b]pyridin-5-amine::US10981879, Example 4

SMILES Nc1cc(SCc2ccccc2Cl)c2nn[nH]c2n1

InChI Key InChIKey=RANNNDFWTLGSRS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492624   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492624(US10981879, Example 4 | 7-((2-chlorobenzyl) thio)-...)
Affinity DataIC50: 60nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent