BDBM492671 7-((4-methoxybenzyl) thio)-3H-[1,2,3]triazolo [4,5-b]pyridin-5-amine::US10981879, Example 9

SMILES COc1ccc(CSc2cc(N)nc3[nH]nnc23)cc1

InChI Key InChIKey=GTWMTMQZOQNMLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492671   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492671(US10981879, Example 9 | 7-((4-methoxybenzyl) thio)...)
Affinity DataIC50: 60nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent