BDBM492716 7-(((5-chloro-3-ethyl-1- methyl-1H-pyrazol-4- yl)methyl)thio)-3H-[1,2,3] triazolo[4,5-b]pyridin-5- amine::US10981879, Example 85

SMILES CCc1nn(C)c(Cl)c1CSc1cc(N)nc2[nH]nnc12

InChI Key InChIKey=WUPQOPHIKZNYTJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492716   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492716(US10981879, Example 85 | 7-(((5-chloro-3-ethyl-1- ...)
Affinity DataIC50: 60nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent