BDBM492717 7-(((1-methyl-5- (trifluoromethyl)-1H- pyrazol-4-yl)methyl)thio)- 3H-[1,2,3]triazolo[4,5-b] pyridin-5-amine::US10981879, Example 86

SMILES Cn1ncc(CSc2cc(N)nc3[nH]nnc23)c1C(F)(F)F

InChI Key InChIKey=TTWCJABMNZRLKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492717   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492717(US10981879, Example 86 | 7-(((1-methyl-5- (trifluo...)
Affinity DataIC50: 60nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent