BDBM492832 7-((1-phenylethyl)thio)- 3H-[1,2,3]triazolo[4,5- b]pyridin-5-amine::US10981879, Example 2

SMILES CC(Sc1cc(N)nc2[nH]nnc12)c1ccccc1

InChI Key InChIKey=KMMHTBDEHUXDAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492832   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492832(US10981879, Example 2 | 7-((1-phenylethyl)thio)- 3...)
Affinity DataIC50: 10nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog #A12222) which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492832(US10981879, Example 2 | 7-((1-phenylethyl)thio)- 3...)
Affinity DataIC50: 10nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent