BDBM492841 US10981879, Example 70::ethyl 5-(((5-amino-3H- [1,2,3]triazolo[4,5-b]pyridin- 7-yl)thio)methyl)-1-methyl- 1H-pyrazole-3-carboxylate

SMILES CCOC(=O)c1cc(CSc2cc(N)nc3[nH]nnc23)n(C)n1

InChI Key InChIKey=LKERVASOOPZZIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492841   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492841(US10981879, Example 70 | ethyl 5-(((5-amino-3H- [1...)
Affinity DataIC50: 50nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog #A12222) which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM492841(US10981879, Example 70 | ethyl 5-(((5-amino-3H- [1...)
Affinity DataIC50: 760nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent