BDBM49288 (5-chloro-2-pyridyl)-[4-(2-thienyl)thiazol-2-yl]amine::5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyridinamine::MLS000064746::N-(5-chloranylpyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine::N-(5-chloro-2-pyridinyl)-4-thiophen-2-yl-2-thiazolamine::N-(5-chloropyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine::SMR000077573::cid_2214576

SMILES Clc1ccc(Nc2nc(cs2)-c2cccs2)nc1

InChI Key InChIKey=OSWCDUQDLSLAGR-UHFFFAOYSA-N

Data  5 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 49288   

TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49288(5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyri...)
Affinity DataEC50:  686nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM49288(5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyri...)
Affinity DataIC50: 620nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetNuclear receptor subfamily 1 group I member 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49288(5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyri...)
Affinity DataEC50: >1.16E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetAryl hydrocarbon receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49288(5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyri...)
Affinity DataEC50:  1.58E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM49288(5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyri...)
Affinity DataIC50: 1.03E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM49288(5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyri...)
Affinity DataIC50: 620nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetProtein skinhead-1(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49288(5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyri...)
Affinity DataIC50: 1.15E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHeat shock protein hsp-16.2(Caenorhabditis elegans)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49288(5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyri...)
Affinity DataIC50: 2.31E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetOxysterols receptor LXR-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM49288(5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyri...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay