BDBM494161 US10988481, Compound 15

SMILES Oc1ccc2C[C@H]3N(CC[C@@]45C(Oc1c24)[C@@H](CC[C@@]35O)NC(=O)c1cccc2cc[nH]c12)C1CC1

InChI Key InChIKey=AGEDNIMOIFKPSV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 494161   

TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

US Patent
LigandPNGBDBM494161(US10988481, Compound 15)
Affinity DataKi:  0.188nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

US Patent
LigandPNGBDBM494161(US10988481, Compound 15)
Affinity DataKi:  0.520nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

US Patent
LigandPNGBDBM494161(US10988481, Compound 15)
Affinity DataKi:  30.4nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent