BDBM494783 N~2~-(4-{N-[(1S)-6-fluoro- 2,3-dihydro-1H-inden-1-yl]- N'-hydroxycarbamimidoyl}- 1,2,5-oxadiazol-3-yl)-N-(2- hydroxypropyl)glycinamide::US10988487, Example 179

SMILES CC(O)CNC(=O)CNc1nonc1\C(N[C@H]1CCc2ccc(F)cc12)=N\O

InChI Key InChIKey=WVNXGNLPHOMCSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494783   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM494783(US10988487, Example 179 | N~2~-(4-{N-[(1S)-6-fluor...)
Affinity DataIC50: 54.1nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
US Patent