BDBM495094 US10995072, Example 61

SMILES OC(c1ncc[nH]1)c1ccc(F)n2ccc(Cl)c12

InChI Key InChIKey=CIPRAUHPZDUZHV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495094   

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM495094(US10995072, Example 61)
Affinity DataIC50: 1.90E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM495094(US10995072, Example 61)
Affinity DataIC50: 3.10E+3nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent