BDBM497488 US11008304, Example 74

SMILES COc1cc(C)c(cc1C(=O)Nc1cccc(n1)-n1nnnc1C(C)C)-c1cnn(C)c1

InChI Key InChIKey=AGSBBSGXZHGQRK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497488   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM497488(US11008304, Example 74)
Affinity DataIC50: 5.5nMAssay Description:The ability (IC50) of compounds to inhibit ASK1 kinase activity was determined by HTRF KinEASE Assay System. ASK1 was purchased from Thermofisher (Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2021
Entry Details
US Patent