BDBM50000796 4-cyclopropylmethyl-10-hydroxy-14-(4-methylene-5-oxotetrahydro-2-furanylmethoxy)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-17-yl acetate::CHEMBL310785

SMILES CC(=O)O[C@]12CC[C@@H](OC[C@@H]3CC(=C)C(=O)O3)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O

InChI Key InChIKey=YGMJUEYNRVHCAT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50000796   

TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000796(CHEMBL310785 | 4-cyclopropylmethyl-10-hydroxy-14-(...)
Affinity DataIC50: 2.80nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000796(CHEMBL310785 | 4-cyclopropylmethyl-10-hydroxy-14-(...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000796(CHEMBL310785 | 4-cyclopropylmethyl-10-hydroxy-14-(...)
Affinity DataIC50: 14nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000796(CHEMBL310785 | 4-cyclopropylmethyl-10-hydroxy-14-(...)
Affinity DataIC50: 25nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed