BDBM50000987 CHEMBL3235251

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1cc(C)ccc1-n1nccn1)\C=C\c1ccc(F)cn1

InChI Key InChIKey=DCHBSRUTSLBOQU-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50000987   

TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000987(CHEMBL3235251)
Affinity DataKi:  3nMAssay Description:Binding affinity to human OX2 receptor in cell membrane by in vitro radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000987(CHEMBL3235251)
Affinity DataKi:  17nMAssay Description:Binding affinity to human OX1 receptor in cell membrane by in vitro radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000987(CHEMBL3235251)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at human OX2 receptor assessed as Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000987(CHEMBL3235251)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human OX1 receptor assessed as Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed