BDBM50001040 6,11-Dimethyl-3-(3-methyl-butyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL2021605

SMILES [H][C@@]12Cc3ccc(O)cc3[C@@](C)(CN1CC1CC1)[C@@H]2C

InChI Key InChIKey=LSQSRZOMUOOWDV-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50001040   

TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  76nMAssay Description:Binding affinity was determined against Opioid receptor kappa 1 obtained from guinea pig brain membranes using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  76nMAssay Description:Binding affinity towards Opioid receptor kappa 1 from guinea pig brain using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  360nMAssay Description:Binding affinity was determined against Opioid receptor mu 1 obtained from guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  360nMAssay Description:Binding affinity towards Opioid receptor mu 1 from guinea pig brain using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity was determined against Opioid receptor delta 1 obtained from guinea pig brain membranes using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity towards Opioid receptor delta 1 from guinea pig brain using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]naltrindole from Opioid receptor delta 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001040(CHEMBL2021605 | 6,11-Dimethyl-3-(3-methyl-butyl)-1...)
Affinity DataKi:  1.24E+3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed