BDBM50001196 CHEMBL610522

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cc(cnc21)-c1ccccc1)ccc3O

InChI Key

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50001196   

TargetDelta-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50001196(CHEMBL610522)
Affinity DataKi:  0.870nMAssay Description:Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50001196(CHEMBL610522)
Affinity DataKi:  3.40nMAssay Description:Antagonist potency measured as Ke = [antagonist]/(IC50 ratio-1) against delta opioid receptor from mouse vas deferens (MVD) using DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50001196(CHEMBL610522)
Affinity DataKi:  14nMAssay Description:Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50001196(CHEMBL610522)
Affinity DataKi:  18nMAssay Description:Binding affinity for Opioid receptor kappa 1 was determined by inhibition of binding of [3H]U-69593 (1.2-2.2 nM) to guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50001196(CHEMBL610522)
Affinity DataKi:  42nMAssay Description:The opioid antagonist potency against PL-107 mu-opioid receptor from guinea pig ileum(GPI).Ke (nM) = [antagonist]/(IC50 ratio-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed