BDBM50001517 1-Ethyl-3,7-dihydro-purine-2,6-dione::CHEMBL127167

SMILES CCn1c(=O)[nH]c2nc[nH]c2c1=O

InChI Key InChIKey=KKWIVMCCCHOXGV-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50001517   

TargetAdenosine receptor A1(Guinea pig)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50001517(CHEMBL127167 | 1-Ethyl-3,7-dihydro-purine-2,6-dion...)
Affinity DataKi:  9.80E+3nMAssay Description:Affinity against adenosine A1 receptor in the brain membranes by the displacement of [3H]CPX.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50001517(CHEMBL127167 | 1-Ethyl-3,7-dihydro-purine-2,6-dion...)
Affinity DataKi:  2.63E+4nMAssay Description:Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Guinea pig)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50001517(CHEMBL127167 | 1-Ethyl-3,7-dihydro-purine-2,6-dion...)
Affinity DataKi:  3.40E+4nMAssay Description:Affinity against adenosine A2 receptor in the brain membranes measured by the displacement of [3H]-CPXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50001517(CHEMBL127167 | 1-Ethyl-3,7-dihydro-purine-2,6-dion...)
Affinity DataEC50:  9.62E+4nMAssay Description:Relaxant activity on the spontaneous tone of isolated guinea pig tracheal ring chains.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed