BDBM50001712 CHEMBL143416::methyl 2-[4-cyclopropylmethyl-17-hydroxy-10-(2-methyloxycarbonylallyloxy)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-yloxymethyl]acrylate

SMILES COC(=O)C(=C)CO[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(OCC(=C)C(=O)OC)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45

InChI Key InChIKey=GVEQIUQAUJPICN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50001712   

TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001712(CHEMBL143416 | methyl 2-[4-cyclopropylmethyl-17-hy...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of opioid receptor mu by displacing 1 nM [3H]DAGO in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001712(CHEMBL143416 | methyl 2-[4-cyclopropylmethyl-17-hy...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Opioid receptor delta 1 by displacing 1 nM [3H]DPDPE in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001712(CHEMBL143416 | methyl 2-[4-cyclopropylmethyl-17-hy...)
Affinity DataIC50: 14nMAssay Description:Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001712(CHEMBL143416 | methyl 2-[4-cyclopropylmethyl-17-hy...)
Affinity DataIC50: 42nMAssay Description:Inhibition of opioid receptor kappa by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed