BDBM50001809 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piperidin-4-yl)-1H-indole::CHEMBL144362

SMILES CN1CCC(CC1)n1c(C)c(-c2ccc(F)cc2)c2cc(C)ccc12

InChI Key InChIKey=JHXVZNYMJMMPEI-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50001809   

TargetAlpha-1A adrenergic receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001809(CHEMBL144362 | 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001809(CHEMBL144362 | 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-...)
Affinity DataIC50: 2.60E+3nMAssay Description:Displacement of [3H]spiperone from Dopamine receptor D2 rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001809(CHEMBL144362 | 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-...)
Affinity DataIC50: 5.30nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50001809(CHEMBL144362 | 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]-Ketanserin from rat cortical membrane 5-HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001809(CHEMBL144362 | 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-...)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]-spiperone from rat striatal membrane D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001809(CHEMBL144362 | 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]prazosin from rat whole brain alpha1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed