BDBM50002243 1-Cyclopropylmethyl-4-(4-nitro-phenoxymethyl)-piperidine;0.75hydrate::CHEMBL136395::CHEMBL47251

SMILES [O-][N+](=O)c1ccc(OCC2CCN(CC3CC3)CC2)cc1

InChI Key InChIKey=XNJAGXCZRUPRKN-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002243   

TargetSigma non-opioid intracellular receptor 1(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002243(CHEMBL47251 | CHEMBL136395 | 1-Cyclopropylmethyl-4...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50002243(CHEMBL47251 | CHEMBL136395 | 1-Cyclopropylmethyl-4...)
Affinity DataKi:  13nMAssay Description:Receptor binding affinity against Sigma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002243(CHEMBL47251 | CHEMBL136395 | 1-Cyclopropylmethyl-4...)
Affinity DataKi:  215nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002243(CHEMBL47251 | CHEMBL136395 | 1-Cyclopropylmethyl-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound was tested in vitro for its binding affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed