BDBM50003021 7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4-propyl-1,4,6,7-tetrahydro-1,3,4,5a,8-pentaaza-as-indacen-5-one::CHEMBL116486

SMILES CCCn1c2nc(nc2c2N[C@H](CC)Cn2c1=O)C12CC3CC1CC(C2)C3

InChI Key

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50003021   

TargetAdenosine receptor A1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50003021(CHEMBL116486 | 7-Ethyl-2-(hexahydro-2,5-methano-pe...)
Affinity DataKi:  0.560nMAssay Description:Tested for binding affinity against Adenosine A1 receptor from rat forebrain membranes, using N6-[3H]- cyclohexyladenosine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50003021(CHEMBL116486 | 7-Ethyl-2-(hexahydro-2,5-methano-pe...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity towards Adenosine A1 receptor using N6-[3H]cyclohexyladenosine in guinea pig forebrain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50003021(CHEMBL116486 | 7-Ethyl-2-(hexahydro-2,5-methano-pe...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity against Adenosine A1 receptor from guinea pig forebrain membranes by N6-[3H]- cyclohexyladenosine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50003021(CHEMBL116486 | 7-Ethyl-2-(hexahydro-2,5-methano-pe...)
Affinity DataKi:  290nMAssay Description:Binding affinity at Adenosine A2 receptor from rat striatal membranes by N-[3H] ethyladenosin-5'- uronamide displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50003021(CHEMBL116486 | 7-Ethyl-2-(hexahydro-2,5-methano-pe...)
Affinity DataKi:  290nMAssay Description:Binding affinity towards Adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide in guinea pig forebrain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed