BDBM50003167 CHEMBL121731::N-(6-Cyclohexylmethyl-7-hydroxy-10-morpholin-4-ylmethyl-4,8,14-trioxo-1,9-dioxa-5-aza-cyclotetradec-3-yl)-3-phenyl-acrylamide

SMILES O[C@@H]1[C@H](CC2CCCCC2)NC(=O)[C@H](COC(=O)CCC[C@H](CN2CCOCC2)OC1=O)NC(=O)\C=C\c1ccccc1

InChI Key InChIKey=YCOIIHDSLBTVOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003167   

TargetRenin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003167(CHEMBL121731 | N-(6-Cyclohexylmethyl-7-hydroxy-10-...)
Affinity DataIC50: 94nMpH: 7.4Assay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed