BDBM50003194 CHEMBL124616::[1-(6-Cyclohexylmethyl-7-hydroxy-10-morpholin-4-ylmethyl-4,8,14-trioxo-1,9-dioxa-5-aza-cyclotetradec-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid 2-[2-(2-methoxy-ethoxy)-ethoxy]-ethyl ester

SMILES COCCOCCOCCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1COC(=O)CCC[C@H](CN2CCOCC2)OC(=O)[C@H](O)[C@H](CC2CCCCC2)NC1=O

InChI Key InChIKey=MBTPMLYQBGFCQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003194   

TargetRenin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003194(CHEMBL124616 | [1-(6-Cyclohexylmethyl-7-hydroxy-10...)
Affinity DataIC50: 0.5nMpH: 7.4Assay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed