BDBM50003473 CHEMBL317193::[4-(3,3-Diphenyl-acryloyl)-piperazin-1-yl]-pyridin-3-yl-acetonitrile

SMILES O=[#6](\[#6]=[#6](/c1ccccc1)-c1ccccc1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](C#N)-c1cccnc1

InChI Key InChIKey=HJESLACBVRVBKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003473   

TargetPlatelet-activating factor receptor(Guinea pig)
J. Uriach & C£A.S.A.

Curated by ChEMBL
LigandPNGBDBM50003473(CHEMBL317193 | [4-(3,3-Diphenyl-acryloyl)-piperazi...)
Affinity DataIC50: 10nMAssay Description:Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
J. Uriach & C£A.S.A.

Curated by ChEMBL
LigandPNGBDBM50003473(CHEMBL317193 | [4-(3,3-Diphenyl-acryloyl)-piperazi...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of PAF-induced platelet aggregation in male rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed