BDBM50004661 CHEMBL316973::[2-(5-Dimethylaminomethyl-furan-2-ylmethylsulfanyl)-ethyl]-(2,4-dinitro-phenyl)-amine

SMILES CN(C)Cc1ccc(CSCCNc2ccc(cc2[N+]([O-])=O)[N+]([O-])=O)o1

InChI Key InChIKey=GWLYGKHENDIOMW-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50004661   

TargetMuscarinic acetylcholine receptor M1(Mouse)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004661(CHEMBL316973 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity against mouse muscarinic acetylcholine receptor M1 using cerebral cortex and [3H]pirenzepineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004661(CHEMBL316973 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of human acetylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004661(CHEMBL316973 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of [3H]N-methylscopolamine to rat muscarinic acetylcholine receptor M2 from heart tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004661(CHEMBL316973 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of human butryl cholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Mouse)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004661(CHEMBL316973 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataKi:  870nMAssay Description:Ability to displace [3H]methylscopolamine ([3H]NMS) from mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Mouse)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50004661(CHEMBL316973 | [2-(5-Dimethylaminomethyl-furan-2-y...)
Affinity DataKi:  1.20E+4nMAssay Description:Ability to displace [3H]methylscopolamine ([3H]NMS) from mouse cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed