BDBM50005364 (3S,4R)3-Methyl-3-(3-methyl-[1,2,4]oxadiazol-5-yl)-1-aza-bicyclo[2.2.1]heptane::CHEMBL171721

SMILES Cc1noc(n1)C1(C)CN2CCC1C2

InChI Key

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50005364   

TargetMuscarinic acetylcholine receptor M1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005364(CHEMBL171721 | (3S,4R)3-Methyl-3-(3-methyl-[1,2,4]...)
Affinity DataEC50:  110nMAssay Description:Compound was tested in vitro for depolarizing response on the rat superior cervical ganglion (mediated by muscarinic acetylcholine receptor M1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005364(CHEMBL171721 | (3S,4R)3-Methyl-3-(3-methyl-[1,2,4]...)
Affinity DataEC50:  13nMAssay Description:In vitro contraction of guinea pig myenteric plexus preparation (mediated by muscarinic acetylcholine receptor M3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005364(CHEMBL171721 | (3S,4R)3-Methyl-3-(3-methyl-[1,2,4]...)
Affinity DataEC50:  14nMAssay Description:In vitro negative chronotropic effect on electrically driven guinea pig atria(mediated by Muscarinic M2 receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed