BDBM50005475 CHEMBL140883::CHEMBL3234246

SMILES O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)Nc1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=DWCKWRDXAXHZKY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50005475   

TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50005475(CHEMBL140883 | CHEMBL3234246)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at Gal4-fused RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50005475(CHEMBL140883 | CHEMBL3234246)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at full-length RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50005475(CHEMBL140883 | CHEMBL3234246)
Affinity DataIC50: 3.09E+3nMAssay Description:Antagonist activity at human His6-tagged RORgamma ligand binding domain (262 to 507 aa) assessed as inhibition of SRC1-4 co-activator peptide recruit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed