BDBM50005556 3-Benzoyloxy-8-benzyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL177269

SMILES COC(=O)C1C2CC[C@H](C[C@@H]1OC(=O)c1ccccc1)N2Cc1ccccc1

InChI Key InChIKey=XYKATAPFAYNVFX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50005556   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005556(CHEMBL177269 | 3-Benzoyloxy-8-benzyl-8-aza-bicyclo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005556(CHEMBL177269 | 3-Benzoyloxy-8-benzyl-8-aza-bicyclo...)
Affinity DataIC50: 77nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005556(CHEMBL177269 | 3-Benzoyloxy-8-benzyl-8-aza-bicyclo...)
Affinity DataIC50: 140nMAssay Description:Inhibition of [3H]BTCP binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005556(CHEMBL177269 | 3-Benzoyloxy-8-benzyl-8-aza-bicyclo...)
Affinity DataIC50: 250nMAssay Description:Inhibition of [3H]GBR-12935 binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005556(CHEMBL177269 | 3-Benzoyloxy-8-benzyl-8-aza-bicyclo...)
Affinity DataIC50: 668nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed