BDBM50005687 1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propionylamino)-2-hydroxy-4-phenyl-butyl]-pyrrolidine-2-carboxylic acid tert-butyl ester::BDBM50010502::CHEMBL115292

SMILES CC(C)(C)OC(=O)[C@@H]1CCCN1C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1

InChI Key InChIKey=UYYUHWSVKOGLPA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50005687   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 51nMAssay Description:In vitro concentration required to inhibit 50% activity of HIV protease was measured (exp 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 300nMAssay Description:Binding activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 450nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme.(value reported by Roche group)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 140nMAssay Description:In vitro concentration required to inhibit 50% activity of HIV protease was measured (exp 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 300nMAssay Description:Binding activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme.(value reported by Roche group)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 51nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme (by Dixon analysis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme.(value reported by Roche group)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed