BDBM50005701 CHEMBL337283::N*1*-[1-Benzyl-3-(2-tert-butylcarbamoyl-pyrrolidin-1-yl)-2-hydroxy-3-oxo-propyl]-2-[(quinoline-2-carbonyl)-amino]-succinamide

SMILES CC(C)(C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1

InChI Key InChIKey=JVBMLUUKYDVROE-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50005701   

TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50005701(CHEMBL337283 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataEC50:  145nMAssay Description:Antiviral activity against HTLV-1 RF infected MT-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50005701(CHEMBL337283 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataIC50: 1.10nMAssay Description:Compound was evaluated for the inhibition of HIV proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50005701(CHEMBL337283 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory potency against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50005701(CHEMBL337283 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50005701(CHEMBL337283 | N*1*-[1-Benzyl-3-(2-tert-butylcarba...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity against HIV protease enzyme.(by Dixon analysis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed