BDBM50006148 5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-oxo-ethoxy]-hexanoylamino}-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid butylamide::CHEMBL297129

SMILES CCCCNC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCC)O[C@@H](Cc1ccccc1)C(=O)N1CCC(CC1)OCOC)C(C)C

InChI Key InChIKey=DZQUVALQGGELBO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006148   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006148(CHEMBL297129 | 5-{2-[1-Benzyl-2-(4-methoxymethoxy-...)
Affinity DataIC50: 8.20nMpH: 7.4Assay Description:In vitro potency against plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006148(CHEMBL297129 | 5-{2-[1-Benzyl-2-(4-methoxymethoxy-...)
Affinity DataIC50: 1.5nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006148(CHEMBL297129 | 5-{2-[1-Benzyl-2-(4-methoxymethoxy-...)
Affinity DataIC50: 1.20nMpH: 6.0Assay Description:In vitro potency against purified renin at a pH of 6.0.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006148(CHEMBL297129 | 5-{2-[1-Benzyl-2-(4-methoxymethoxy-...)
Affinity DataIC50: 8.20nMpH: 7.4Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed