BDBM50006285 CHEMBL3234699::US8846730, 18

SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2ccccn2)C(F)(F)F)s1

InChI Key InChIKey=NYHRWJVBTARQAN-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006285   

TargetCannabinoid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50006285(CHEMBL3234699 | US8846730, 18)
Affinity DataEC50:  1nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Rat)
Abbvie

US Patent
LigandPNGBDBM50006285(CHEMBL3234699 | US8846730, 18)
Affinity DataKi:  6nM ΔG°:  -11.4kcal/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50006285(CHEMBL3234699 | US8846730, 18)
Affinity DataKi:  20nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50006285(CHEMBL3234699 | US8846730, 18)
Affinity DataEC50: >2.70E+4nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed