BDBM50006324 6-Carboxymethyl-12-(3-guanidino-propyl)-15-(4-hydroxy-benzyl)-1,5,8,11,14,17-hexaoxo-1lambda*4*-thia-4,7,10,13,16-pentaaza-cyclooctadecane-3-carboxylic acid::CHEMBL302465

SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CS(=O)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O)C(O)=O

InChI Key InChIKey=DMXRDQJVBMEHPP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006324   

TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50006324(CHEMBL302465 | 6-Carboxymethyl-12-(3-guanidino-pro...)
Affinity DataIC50: 4.80nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50006324(CHEMBL302465 | 6-Carboxymethyl-12-(3-guanidino-pro...)
Affinity DataIC50: 4.80nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50006324(CHEMBL302465 | 6-Carboxymethyl-12-(3-guanidino-pro...)
Affinity DataIC50: 450nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50006324(CHEMBL302465 | 6-Carboxymethyl-12-(3-guanidino-pro...)
Affinity DataIC50: 450nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed