BDBM50006612 CHEMBL3235488

SMILES Ic1ccc2c(c1)-c1ccc(cc1S2(=O)=O)N1CCN2CCC1CC2

InChI Key InChIKey=FVYGPOGSXRAZEB-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50006612   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006612(CHEMBL3235488)
Affinity DataKi:  6.5nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat cortical membrane alpha7-nAChR after 150 mins by gamma-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006612(CHEMBL3235488)
Affinity DataKi:  477nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006612(CHEMBL3235488)
Affinity DataKi:  784nMAssay Description:Displacement of [3H]epibatidine from alpha2beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006612(CHEMBL3235488)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006612(CHEMBL3235488)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006612(CHEMBL3235488)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006612(CHEMBL3235488)
Affinity DataKi:  9.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed