BDBM50006613 CHEMBL3235480

SMILES Fc1cccc2-c3ccc(cc3S(=O)(=O)c12)N1CCN2CCC1CC2

InChI Key InChIKey=JIGWWGDIEUWCOR-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50006613   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi:  0.370nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat cortical membrane alpha7-nAChR after 150 mins by gamma-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-alpha-BTX from rat alpha7 nAChR incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]GR65630 from human 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi:  562nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi:  562nMAssay Description:Binding affinity to nACh alpha7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi:  709nMAssay Description:Displacement of [3H]epibatidine from alpha3beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006613(CHEMBL3235480)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha2beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed