BDBM50006615 CHEMBL3235483

SMILES Fc1c2c(ccc1N1CCN3CCC1CC3)-c1ccccc1S2(=O)=O

InChI Key InChIKey=BKRDDYIAVADMIJ-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50006615   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006615(CHEMBL3235483)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat cortical membrane alpha7-nAChR after 150 mins by gamma-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006615(CHEMBL3235483)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006615(CHEMBL3235483)
Affinity DataKi:  292nMAssay Description:Displacement of [3H]epibatidine from alpha2beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006615(CHEMBL3235483)
Affinity DataKi:  678nMAssay Description:Displacement of [3H]epibatidine from alpha3beta2-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006615(CHEMBL3235483)
Affinity DataKi:  838nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006615(CHEMBL3235483)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50006615(CHEMBL3235483)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed