BDBM50006818 CHEMBL3236951

SMILES Cc1c(-c2cn(CC(C)(C)C)c(=O)c3ccccc23)c2cc(F)ccc2n1CC(O)=O

InChI Key InChIKey=PQDMDOPPJQYUJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50006818   

TargetProstaglandin D2 receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006818(CHEMBL3236951)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human recombinant CRTh2 expressed in CHO-K1 cells by cAMP TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006818(CHEMBL3236951)
Affinity DataIC50: 18nMT: 2°CAssay Description:Antagonist activity at CRTh2 in human peripheral blood assessed as inhibition of PGD2-induced eosinophil shape change at room temperature by flow cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed