BDBM50006978 4-[2-(3-Phenyl-propylamino)-propyl]-phenol::CHEMBL20807::US11999676, Compound 37

SMILES CC(Cc1ccc(O)cc1)NCCCc1ccccc1

InChI Key InChIKey=ZOAOPNBKLJOIJY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006978   

TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006978(CHEMBL20807 | 4-[2-(3-Phenyl-propylamino)-propyl]-...)
Affinity DataKi:  10nMAssay Description:Opioid activity in terms of inhibition of [3H]dihydromorphine binding to opioid receptor mu in rat brain membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006978(CHEMBL20807 | 4-[2-(3-Phenyl-propylamino)-propyl]-...)
Affinity DataKi:  25.7nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM50006978(CHEMBL20807 | 4-[2-(3-Phenyl-propylamino)-propyl]-...)
Affinity DataKi:  33nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandPNGBDBM50006978(CHEMBL20807 | 4-[2-(3-Phenyl-propylamino)-propyl]-...)
Affinity DataKi:  820nMAssay Description:Synaptic vesicles were prepared from rat brain using a modification of a previously described procedure (Teng et al., 1998). Briefly, fresh whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent