BDBM50007040 2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl]-thiazole::CHEMBL20953

SMILES COC1(CCc2ccc(OCc3ccc4ccccc4c3)cc12)c1nccs1

InChI Key InChIKey=PHWUGPWQJTXVQO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50007040   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 14nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 2.00E+4nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 800nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 800nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 14nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 30nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory concentration against 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed