BDBM50007042 2-{Methoxy-[3-(naphthalen-2-ylmethoxy)-phenyl]-methyl}-thiazole::CHEMBL304320

SMILES COC(c1nccs1)c1cccc(OCc2ccc3ccccc3c2)c1

InChI Key InChIKey=XUMOXZBAIWUITO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007042   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007042(CHEMBL304320 | 2-{Methoxy-[3-(naphthalen-2-ylmetho...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007042(CHEMBL304320 | 2-{Methoxy-[3-(naphthalen-2-ylmetho...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007042(CHEMBL304320 | 2-{Methoxy-[3-(naphthalen-2-ylmetho...)
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007042(CHEMBL304320 | 2-{Methoxy-[3-(naphthalen-2-ylmetho...)
Affinity DataIC50: 1.20E+4nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed