BDBM50007227 1-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one::CHEMBL319166

SMILES Cn1c2cc3ccccc3nc2[nH]c1=O

InChI Key InChIKey=PAFMJYHJVIDVQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007227   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007227(CHEMBL319166 | 1-Methyl-1,3-dihydro-imidazo[4,5-b]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hydrolysis of c-AMP phosphodiesterase in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007227(CHEMBL319166 | 1-Methyl-1,3-dihydro-imidazo[4,5-b]...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of cGMP hydrolysis by human platelet phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed